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New Medical Frontier: The Growing Importance of Good Gut Health

We don’t often think about what is inside our gut, but there is growing scientific evidence suggesting that good gut bacteria – or gut flora health – is paramount to a healthy life. Collectively known as microbiota, they impact everything from metabolism and sleep regulation, to mood and the immune system. And since these microbiota are a key to health, they represent a whole new medical frontier. That is why it is so important to understand how to restore healthy gut flora.

New Medical and Diet Frontier The Growing Impact of Gut Bacteria on Living a Healthy Life
What is this growing scientific evidence suggesting that good gut bacteria – or gut flora health – is paramount to a healthy life?

For too long the word “bacteria” has had negative connotations. But thanks to science, we have a better understanding of the importance of gut health. Now we know that gut bacteria and health go hand in hand.

What is Gut Flora and the Importance of Gut Health

Gut flora is a scientific term that is used to describe the bacteria (or microorganisms) that exist within the human body in our intestines. These microorganisms, which are primarily bacteria, populate our digestive track. Scientists and medical professionals are increasingly examining the link between proper gut flora balance and our health, especially in relation to disease vulnerability.

The importance of gut health can be seen in how microbiota directly affects a person's well-being.
The importance of gut health cannot be understated, as evidenced by the impact microbiota has on the body.

The resulting data is showing that a person’s diet and genetic background, as well as other factors (drugs, pesticides, pollutants), link directly to the metabolic performance of the gut flora. This metabolic performance, in turn, impacts health. And the number of animal- and human studies that shed light on the impact of gut flora on human health is increasing.

Gut Bacteria and How to Restore Healthy Gut Flora

Gut flora is essential to proper metabolism and the prevention of disease. More bacteria are living in your body than there are human cells, and they weigh as much as three pounds, approximately equivalent to the weight of the brain. These thousand species of bacteria each play a different role in your body. They act like a completely different organ and play a crucial role in regulating health outcomes.

From our birth, the gut flora begins to affect our body as microbes pass through the mother’s birth canal. As our body ages, the microbiome diversifies and evolves into many different types of species. The larger the diversity of gut flora, the better it is generally for your health. Also, many of our most essential functions are regulated by it, including fiber digestion, an active immune system, and brain health. Recent research also highlights that an overabundance of different bad metabolites is a direct link to disease and weight gain.

The Growing Business of Making Drugs from the Gut Flora

Because of the growing understanding of the importance of gut health, many established businesses and start-ups are focusing on new therapies based on microbes. After all, if gut bacteria and health go hand in hand, then illness prevention and treatment can’t be too far behind.

One of these companies exploring the space is Cambridge, MA-based Seres Therapeutics. The company is researching and building a new class of medicine that utilizes live bacteria to treat disease. They believe that by focusing on the functional deficiencies in the microbiome, a condition known as dysbiosis, they can pinpoint functional differences and create new Ecobiotic drugs.

Another company, Viome, is using technology developed by the Los Alamos National Lab to identify the strains and species of gut flora. They believe there is no one-size-fits-all diet for each person’s good health. Viome offers an in-home kit that collects samples which are analyzed to determine the nutrients and toxins in your body. The company then uses artificial intelligence to recommend the right food mix for an individual based on their specific needs. The goal is to be able to prevent disease through the adoption of a personalized nutritional plan that is based on deep molecular analysis. They are employing a subscription-based service model and they soon will be offering a complete diagnostics service.

Want to know how to restore healthy gut flora? Viome is figuring that out.

The Importance of Gut Bacteria and Health… And Diet

Society is entering a new era where we can increasingly modify health through gut flora. And this is especially true via the food that we eat. New scientific breakthroughs can measure the effects through our gut bacteria.

But the flipside to the diet aspect is the adverse effects caused by drugs, pesticides, and processed food ingredients. Their impact on gut bacteria and health are becoming clearer.  A strong microbiota full of good bacteria is paramount to a more enriched life. Of course, a person can’t take probiotics to halt diabetes or treat cancer. But leading experts, like Seres Therapeutics and Viome, are providing the research needed to determine the precise types of microbiomes that may lead to or prevent specific ailments.

If you are what you eat, then being well means more than just eating healthy. It means eating healthy for your gut.

In our series on gut bacteria and health, Bold Business will be covering topics ranging from the impact on diabetes, Alzheimers, and cancer to causes of poor gut flora.

Sustainable Transport Solutions —Mobilizing the World’s Sustainability Goals

Awareness and action for sustainable development have accelerated in recent years. Today, one of the most important global initiatives is the compilation of Sustainable Development Goals.  Set by the United Nations in 2015, these goals aim to protect the planet and improve the quality of life worldwide.  Transportation is a major driving force in achieving these targets. Its impact and influence spans across other objectives. These include health improvement, pollution reduction, energy efficiency, and economic growth. The sector’s role is substantial for implementing measures for sustainable transportation infrastructure. In fact, if these measures succeed, they can deliver savings of up to $70 trillion by 2050. Clearly, there is a tremendous need for companies and organizations to implement sustainable transport solutions.

The Global Impact of the Transport Industry

Transportation is fundamental to meeting the personal and economic needs of individuals. It allows access to services and facilities that contribute to healthy and fulfilled lives. Examples of these are jobs, markets, and social interaction, among others. Transport development links people, connects communities and facilitates trade. Thus, it has the power to drive sustainable development. As a result, sustainable transport solutions are the center of various international discussions. Topics range from vehicle emissions to green supply chain management practices.

Despite the benefits of transport development, there are also negative consequences. The industry is part of several environmental, social and governance issues.

23 percent of energy-related greenhouse gas emissions come from transportation. Road accidents cause 1.24 million deaths every year. Traffic congestion is a burden on the economy of many countries. It accounts for 0.7 percent of the GDP in the United States. In Europe, it’s 2 percent. In some cities of emerging economies like Beijing, São Paulo and Lima, it’s as high as 10 percent. It’s no wonder that developing a sustainable transportation infrastructure has become a global priority.

Taking Action for Sustainable Transportation Infrastructure

Greener transport is a must to achieve the Sustainable Development Goals. An expert panel delivered a report to former U.N. Secretary-General Ban Ki-moon about this matter. Called ‘Mobilizing Sustainable Transport for Development‘, the report gave recommendations for sustainable transport solutions. These include better planning, increased funding, improved safety standards, and reduced emissions.

During the presentation of the report in 2016, former Secretary-General Ban Ki-moon stated that sustainable transport solutions can solve global transportation issues. “The answer to these problems is not less transport—it is sustainable transport,” he noted, “We need more systems that are environmentally friendly, affordable and accessible.”

Sustainable Transport Solutions —Green Innovations from Companies

The United Nation’s High-Level Advisory Group on Sustainable Transport also urged action. “Transport can build prosperity in the broadest sense, enhancing the quality of life for all while protecting the environment and fighting climate change,” said Martin Lundstedt, co-chair of the group and CEO of Volvo. “We need bold innovation and a true partnership among governments, civil society, and the private sector.”

Transport companies around the world are aware of the industry’s impact. Sustainable transport solutions are no longer optional. They have become an integral part of the strategy and mission for many businesses.

Thanks to technology, more innovations are possible. Sustainable transport solutions continue to emerge. Shared mobility, autonomous driving, and electric vehicles are just a few examples.

Sustainable Transportation Infrastructure

Here are some companies that are making strides in green transport development:

  • Neste is an oil refining and marketing company from Finland. The company is the world’s largest producer of renewable diesel refined from waste and residue. They also provide sustainable transport solutions to the aviation and plastics industries. Neste is on the Global 100 list of the most sustainable companies in the world for 2018.
  • LanzaTech is a biotech startup that turns carbon emissions into ethanol. When blended with gasoline, it reduces the amount of fuel used by cars. The company partnered with Virgin Atlantic to produce jet fuel made from carbon waste.
  • Workhorse is a technology company that designs battery-electric vehicles. These include trucks, aircraft, and drones. Workhorse contributes to making the shipping industry greener through sustainable transport solutions. Monitoring systems enable fleet operators to optimize energy and route efficiency. This case means their delivery vehicles are less harmful to the environment.
  • CGON is a British manufacturer that focuses on hydrogen additive technology. It can slash engine emissions by as much as 80 percent. The additive can work on any fossil fuel as well. Examples are petrol, diesel, and LPG. In line with other sustainable transport solutions, units are also 100 percent recyclable.
  • EasyMile is a French firm that specializes in autonomous vehicles. The company provides sustainable transportation solutions through driverless bus technology. The shuttles aim to improve road safety. Algorithms also allow increased fuel efficiency. EasyMile’s buses already transport passengers in cities across Europe and North America.

 

Transforming Transport Development through Investments

Funding plays an important role in sustainable transport development. Former U.N. Secretary-General Ban Ki-moon underscored, “It takes investments to see results. That means mobilizing funds from a variety of sources. Public-private partnerships are indispensable.” The continued support of stakeholders and investors in the transport industry is truly a must.

Moreover, transport businesses that have strong sustainability agendas stand to gain a competitive edge. Customers and investors are sure to recognize their efforts. They would be the preferred choice versus companies who are not that eco-friendly. Through sustainable transport solutions, businesses can turn the sector’s impact on society into a positive and lasting one.

Sources:

How can we promote sustainable infrastructure?

How These 5 Key Industries Can Advance Sustainable Development Goals

Sustainable transport

Experts Urge Mobilizing Sustainable Transport for SDGs

The Environmental Impacts of Transportation

The Growing Impact of Gut Bacteria on Living a Healthy Life Cartoon

New Medical and Diet Frontier The Growing Impact of Gut Bacteria on Living a Healthy Life
What is this growing scientific evidence suggesting that good gut bacteria – or gut flora health – is paramount to a healthy life?

Startup Companies in New York City —Bold Business’ List of the Top 12

As a prominent hub for innovation, New York City boasts a dynamic startup scene. In fact, the Big Apple is home to over 6,300 startup companies. This fact means it’s the second largest startup ecosystem in the world. In 2017, investments for startup companies in New York reached over $12 billion. Though often compared to Silicon Valley, New York has many distinguishing qualities that make it one of the best places to launch a startup and for creating the top startups in NYC.

A Vibrant Landscape that Breeds Success Creating Top Startups in NYC

Startup companies in New York City enjoy several advantages other than the growing venture capital spending. The city’s famous grid and population density provide accessibility and convenience. Clients, investors, partners, and talent are mostly a few subway stops away. The tight-knit community leads to faster deals and better collaboration.

Another notable advantage that New York City has for startups is its diversity. The city has an eclectic mix of industries. This includes finance, media, and fashion, among many others. As a result, startup companies in New York City have ample ground for cross-pollination of ideas. There is also greater demographic diversity than anywhere else. The workforce there has talented individuals across genders and races. A study even named New York as the best city worldwide for starting a female-led company. While many criticize Silicon Valley for being homogeneous, New York City entrepreneurs have exposure to a breadth of views. They get a better perspective when it comes to running their businesses.

New York Startups Fuel Innovation

Moreover, New York’s ecosystem fuels innovation. This case is vital to the success of many startup companies. Ajay Singhal, a local entrepreneur, and partner at On the Right Track Systems Inc. describes the business landscape in this way:

“The vibrancy offered by New York City is unique. Its no-nonsense, fast-talking, straight-to-the-point, business-friendly environment is what sets it apart and makes it a major international destination.”

The Bold Business staff compiled our list of the Top 12 Startup Companies in New York. In conducting our research, we considered a number of factors including but not limited to:

  • Revenue and the potential to create future revenue
  • The leadership of the organization
  • Social Impact the business is making
  • How they rank in the competitive landscape
  • The uniqueness of the solution
  • Traction of the brand or product

Top 12 Startup Companies in New York 

WeWork

Building communities with innovative shared workspaces

WeWork Companies Inc. provides collaborative office spaces to a community of entrepreneurs, freelancers, startups, small companies and large enterprises. Miguel McKelvey and Adam Neumann founded the 8-year-old company. As a leader in the “space as a service" segment, WeWork uses data to shape its offices. Such data includes information on work habits and areas of high productivity. With a total of $12.1 billion in funding, WeWork aims to position itself as the foremost expert on offices. It’s one of the most popular startup companies in New York. As of September 2018, the company became the largest holder of real estate in Manhattan. WeWork’s customer base includes Microsoft, Salesforce, Samsung and Facebook.
Knotel

Providing flexible, custom built offices

Knotel Inc. seeks to reinvent the commercial real estate market by leasing custom-built spaces under flexible terms for a markup. With its Agile HQ™ Platform, the company offers scalable and adaptable office space solutions that can grow or shrink on demand, based on the needs of its clients. Founded by Amol Sarva and Edward Shenderovich in 2016, Knotel has raised a total of $160 million from A-list investors. It's also one of the fastest-growing startup companies in New York, with a 318 percent growth rate for 2018. The company also operates in San Francisco, Los Angeles, London, Berlin and São Paulo. Knotel’s member network includes Starbucks, Netflix and The Body Shop.
Transfix

Cutting down waste by matching truckers with shipments

Trucking is a fragmented industry. In fact, truckers in the U.S. drive over and above 29 billion miles with empty or partial truckloads. Transfix Inc., one of the top startup companies in transportation today, aims to solve this. Its app helps match carriers with freight, thus saving time and cutting down waste. Machine learning powers the company’s fleet management system. It enables users to track shipments, chat with drivers, and even calculate fuel taxes. Founded by Drew McElroy and Jonathan Salama in 2013, Transfix has a total of $78 million in funding. Barnes & Noble, Unilever and Anheuser-Busch are among Transfix’s roster of clients.
Maven

Ensuring women have access to high-quality health care

Maven Clinic Co. is part of a growing list of startup companies in New York that provide health care services through a mobile app. The company is focused on women, run by women, and funded by women. Founder Kate Ryder built Maven on the belief that health care is a necessity, not a luxury. The platform connects users to a network of 1,300 health specialists. It also allows them to book video appointments and receive prescriptions 24/7. Since launching in 2015, Maven has delivered care to almost 200,000 patients. It continues to boost its services with a total financing of $42 million. It’s one of the top startup companies today with women at the core of operations.
Zola

Modernizing weddings with technology

Zola Inc. first launched as an e-commerce site for wedding registries. It allows users to build personalized pages. Notable features include digital gifts and group gifting. Founded by Shan-Lyn Ma and Nobu Nakaguchi in 2013, the startup has recently expanded into an all-in-one wedding planning platform. Now, couples can also build websites, manage guest lists, and track RSVPs. Zola continues to grow as one of the most successful startup companies in New York, having raised a total of $140.8 million.
Candid Co.

Improving dental health at a lower cost

Traditional braces can cost up to $3,000 to $4,000. Candid Care Co. Inc. provides a more affordable alternative: a subscription for clear aligners at only $88 a month. It’s one of the startup companies currently shaking up the dental industry. Candid also diagnoses, treats and monitors orthodontic cases through modern telehealth practices. The direct-to-consumer approach eliminates the need for dental visits to straighten teeth. Moreover, the insurance plans of a number of patients even cover part of the cost. Launched in 2017 with Nick Greenfield as the founder, it’s among the startup companies in New York to watch out for. Candid has raised a total of $17 million from its investors, which also include orthodontists
Drone Racing League

Bringing a high-flying sport into the mainstream

Drone racing is gaining worldwide popularity. Currently, the most established player in the space is Drone Racing League Inc. (DRL). DRL features custom-built, remote control drones that race through three-dimensional courses. Speeds reach up to 90 miles per hour. During the league's most recent season, over 75 million fans tuned in to watch online and on TV via ESPN. Launched in 2015, DRL has technology at the center of its operations. It even recently launched an autonomous racing series using artificial intelligence. With total funding of $32 million, DRL have sponsors and investors that include Sky UK and the U.S. Air Force. The company founded by Nicholas Horbaczewski is not only considered as one of the top startup companies in New York, but it’s also known as an international leader in drone racing.
The Players' Tribune

Connecting athletes to fans through engaging stories

Former Major League Baseball player Derek Jeter teamed up with Jaymee Messler to build The Players' Tribune. The new media platform allows athletes to tell first-person stories directly to fans. It also creates podcasts, videos, player polls and other written pieces. The Players' Tribune Inc. is now one of the most well-known startup companies in the field. Featuring topics across different sports, it engages fans with unique insights from athletes. The Players' Tribune is one of the startup companies in New York poised for success, with investors including sports personalities such as Kevin Durant, Kobe Bryant and Blake Griffin. The company has raised a total of $58 million since its launch.
Eligible

Automating the medical insurance process

Eligible Inc. connects health care systems to insurance payments through modern APIs. It determines whether a patient's insurance will cover a doctor visit. Founder Katelyn Gleason saw the need to organize the process. Many patients were paying more just for filling out the wrong forms. Now, the company's software automates eligibility for over 2,000 insurance companies. They cover more than 90 percent of the insured U.S. population. Zocdoc, Cleveland Clinic and Oscar are among those who use Eligible's service, with investments amounting to $25.2 million. Eligible saves money for patients, doctors and insurance companies alike. This makes it one of the top startup companies in the medical billing space.
Call9

Reinventing emergency medicine in nursing homes

Call9 Inc. powers health care service that delivers emergency care in nursing homes and rehabilitation centers. The startup's high-touch technology platform makes this possible. Upon activation, Call9's on-site clinical care specialists rush to the patient's bedside to provide medical attention. The platform minimizes unnecessary hospital visits in 80 percent of patient encounters. This number leads to an estimated $8 million in savings per year. Its innovative model defines new standards for telemedicine. Call9, considered as one of the most notable startup companies in New York, was founded by Xiao Song Mu and Timothy C. Peck, MD. It has raised $34 million since launching.
Oscar

Using technology to humanize health insurance

Oscar Insurance Corp. is a disruptor in health care insurance. Most insurers generally use medical data for billing purposes. Oscar, on the other hand, shares it with patients. Its app enables users to track doctor visits, drug purchases and lab work. In addition, the platform provides telemedicine services. The insurance company has received praise for its tech-savvy, customer-centric business model, making it one of the leading startup companies in the medical space. Currently valued at $3.2 billion, Oscar's investors include two branches of Google's parent company, Alphabet. Joshua Kushner, Mario Schlosser and Kevin Nazemi are the founders of the 6-year-old startup.
Better Mortgage

Transforming the home finance process

Better Mortgage Corp. is on a mission to make home finance better for all Americans. It offers affordable, accessible and transparent lending services to prospective home buyers. The company digitizes every step of the financing process through better.com, an intuitive online platform. With Vishal Garg as the founder and CEO, Better has raised a total of $45 million since its launch. It's one of the fastest-growing startup companies in New York. In fact, it was able to increase its customer base by roughly 400 percent year-over-year in 2017. With the ability to perform pre-approvals within the span of three to five minutes, Better is among the top startup companies today that are helping people take control of one of the most important financial decisions they will ever face in their lives.

New York Startups Offer Continuous Growth in a Dynamic Ecosystem

A strong cycle of talent and capital is what makes a startup ecosystem successful. The steps include discovery, funding, scaling and exiting. Such cycle continues to grow and gain momentum in New York. It accounts for the expanding list of the city’s flourishing startups.

Startup companies in New York can expect more promising investments ahead. “NYC is creating the infrastructure to grow industries of the future,” says Ryan Birchmeier, spokesman for the New York City Economic Development Corporation.

“This work is focused on ecosystem building that will attract new venture capital investment, grow startups, increase international expansions and create good-paying jobs for New Yorkers.”

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