Bold Business Logo

Gut Health: Can Probiotics Lower Cholesterol Levels for a Healthy Heart?

Cardiovascular disease is the leading cause of death, and by 2030 it can affect approximately 23.6 million people worldwide. The culprit: high levels of bad cholesterol. Accordingly, researchers are continuously exploring ways to manage cholesterol levels. One potential measure gaining traction in recent years is the consumption of probiotics. Findings from several studies reveal that certain Lactobacillus strains can reduce cholesterol tied to heart disease risk. As a result, the global market for probiotics will likely generate up to $65.87 billion in revenue by the end of 2024. If probiotics lower cholesterol levels – as research suggests –  then one of the most important benefits of taking probiotics is how it promotes heart health.

That would indeed be a tough benefit to ignore.

JoAnn E. Manson quoted
There is a direct correlation between gut health and heart health, which means there’s a correlation between probiotics and cholesterol.

Probiotics and Cholesterol: The Relationship

Probiotics are live bacteria naturally generated from the process of fermentation. Lactobacilli are among the most well-known types. Generally, people consume probiotics through supplements or foods like yogurt, and they add to the population of healthy microbes in the gut. Maintaining the balance between good and bad bacteria is also one of the proposed benefits of taking probiotics.

Probiotics lower cholesterol levels in several ways. They normalize cholesterol absorption through a binding process and make bile acids that can metabolize fat and cholesterol. Certain strains can also produce short-chain fatty acids. Such compounds can help prevent the formation of cholesterol in the liver.

a photo with the company names with a translucent background image of a microscope used in the ongoing research about the question whether probiotics lower cholesterol levels or not
A few companies in the space are forging ahead, armed with the knowledge that the benefits of taking probiotics include heart health.

Bold Businesses Forging Ahead in the Probiotics and Cholesterol Segment

A number of companies have armed themselves with the knowledge that probiotics and cholesterol are tied together. And with that knowledge, they have forged ahead.

UAS Laboratories Inc. is one of the pioneers in the space. The biotech company cultivates probiotics with benefits beyond digestive support. In 2014, UAS Labs acquired Micropharma Limited, and the latter’s researchers developed the Lactobacillus reuteri strain. These probiotics lower cholesterol levels by producing bile salt hydrolase, which breaks apart bile acids. Consequently, the process aids the normalization of dietary and biliary cholesterol absorption.

Another company that studies how probiotics lower cholesterol levels is OptiBiotix Health PLC. The life sciences company develops microbial strains, compounds and formulations that modulate the microbiome.

a photo of a rubber heart beside apples and a jar of honey amid the ongoing research about the question of whether probiotics lower cholesterol levels or not
What are the benefits of taking probiotics? And what’s the connection between probiotics and cholesterol?

Other Offerings in the Sphere of Probiotics and Cholesterol 

United Kingdom-based company ProVen Probiotics is also active in the sphere of developing probiotics products designed for usage in one’s pregnancy, infancy, childhood and even adulthood.

Founder and Managing Director Dr. Nigel Plummer has developed the Lab4 bacteria strain that the company uses in its products.

Finally, there is ProTrea. The company’s product ProTrea Cholesterol Health Probiotic contains five scientifically-researched blend of the Lactobacillus and Bifidobacterium strains. It’s designed and developed to support healthy gut bacteria growth and bring about a healthy level of cholesterol in the body.

Recommendations for Future Research and on the Benefits of Taking Probiotics

While there’s a growing number of evidence that probiotics lower cholesterol levels, further research is still a must. It’s necessary to determine and clarify which probiotic strains are the most effective. Advice for the most ideal doses is also imperative. Moreover, researchers must find out which groups would best reap the benefits of taking probiotics. The participants of existing trials predominantly have mildly high levels of LDL cholesterol.

a photo of numerous test tubes with "LDL-C Test" labels on them amid the ongoing research about the question of whether probiotics lower cholesterol levels or not, and the benefits of taking probiotics
There is evidence that probiotics lower cholesterol levels, but further, continuous research on the benefits of taking probiotics and on the connection of probiotics and cholesterol are still a must.

The fact that probiotics lower cholesterol levels is promising.

However, they are still not part of general diet guidelines for cardiovascular health.

“People know probiotics for digestive health. They don’t associate them with heart health. It’s time to recognize their potential role as a simple and natural tool in cholesterol management.” – Douglas B. DiRienzo, PhD, President of Quadrant Nutrition

For more on probiotics for gut health, read this article on probiotics as potential gut health allies. Also, check out this Bold Business interview with Dr. Steven Gundry, a world-renowned expert on the subject of gut health and its importance.

The Blue Economy: The Growing Demand for Water Desalination and Aquaculture Systems

About 70 percent of the Earth is covered in water, but out of the 1.4 billion cubic kilometers available, only about 200,000 is freshwater. That’s bad. Why? Because by 2030, current water supplies will only meet about 60 percent of the global demand. This certainly makes for a Blue Economy problem that needs a bold solution. Thankfully, the answer may lie in water desalination and aquaculture systems that mitigate the need for depleting freshwater reserves.

The water desalination market is expected to expand tremendously in the coming years. In fact, some estimates suggest that the aquaculture systems space could reach $35 billion within 10 years. And this growing demand is driving new companies – like Forward Water Technologies, Saltworks, and Real Tech Inc. – to develop innovative solutions.

aquaculture systems, logos of companies with desalination solutions
Some innovative businesses are shaping the future of water desalination and aquaculture systems.

More People, More Problems

The math is pretty simple: an increase in human population has led to an increase in the demand for water. And it’s not just drinking water that’s at a premium, it’s also the kind of water needs that arise from industry. While drinking water needs for global societies are at the top of the list, water is integral to agricultural production. As a matter of fact, 70 percent of all water used involves agricultural activities for both crops and livestock. Available surface water and drinking water are thus resources that water desalination and aquaculture systems can prove vital to.

These are not the only pressures encouraging advances in water desalination platforms. Significant demand also exists in various industrial sectors as it relates to wastewater management. Water desalination is being advanced in many industries to change contaminated water into safe, clean water. The industries with the highest demand in this regard include oil/gas, automakers, aerospace, as well as municipalities. In addition to producing clean water, these new aquaculture systems save billions of dollars in waste processing and environmental effects.

C. Howie Honeyman quoted
Forward Water Technologies is among the foremost companies making waves in the water desalination and aquaculture systems space.

Bold Businesses Providing Water Desalination Solutions

From drinking water to wastewater decontamination, several water desalination startups have made an impact on current aquaculture systems. Here’s a closer look at a few of the aforementioned businesses making bold moves in this space:

  • Forward Water Technologies – Founded by GreenCentre Canada in conjunction with Queens University in Ontario, this company is a true innovator in water desalination. The company currently manages wastewater and provides fresh water for reuse for various industries. Furthermore, they offer these services in an automated and scalable fashion for a variety of aquaculture systems.
  • Saltworks Technologies – Based in Richmond, Canada, this water desalination startup provides and installs small modular units to industries. These modules use reverse osmosis and an electrodialysis reversal platform to remove salt in industrial wastewaters. As a result, these customized water desalination modules save companies billions of dollars in aggregate. In addition, the units utilize artificial intelligence to minimize energy use and maximize quality.
  • Atlantis Technologies – This aquaculture systems company evolved out of a project for the U.S. Army. When tasked with water desalination to provide troops drinking water, the company resulted in inventing a patented RDI supercapacitor platform. Saltwater passes through two oppositely-charged supercapacitors, which pull the salt from the water. Today, this platform is used to treat wastewater but has been utilized for drinking water as well.
  • Real Tech Inc. – Originally founded in 2004, Real Tech Inc. has been scaling its aquaculture system technologies for more than a decade. The company now works not only with various industries but also with municipalities in drinking water and wastewater management. Its process involves the use of optical sensors to detect and remove ions and contaminants.
Bill Bartley - CEO, Evapco
One important facet of the Blue Economy is the rising need for water conservation – which water desalination and aquaculture systems aim to tackle.

Opportunities for Future Innovations in Water Desalination

At present, the greatest demand for water desalination is within various industrial sectors. Likewise, municipalities are in need of these services as urban populations swell. But estimates suggest that by 2050 roughly five billion people will be experiencing water shortages globally.

This data will shift the need for innovations from wastewater management to drinking water supplies. At the same time, the need for aquaculture systems that utilize lower energy and provide zero emissions will also increase.

Given this, aquaculture system needs will continue to evolve and change in the years to come. Many bold businesses are addressing today’s challenges related to aquaculture systems. But ample room for future innovations in water desalination and other areas still exist. And while public policies help, it will likely be up to business innovations to lead the way in this pursuit.

 

For more on Bold Business’ series on the Blue Economy, check out these stories on Deep Seabed Mining and Creating a Sustainable Future.

How can we help?